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William H Tepp Selected Research

Botulinum Toxins (Botulinum Toxin)

1/2021Posttranslational Regulation of Botulinum Neurotoxin Production in Clostridium botulinum Hall A-hyper.
9/2019Comparative functional analysis of mice after local injection with botulinum neurotoxin A1, A2, A6, and B1 by catwalk analysis.
10/2018Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6.
1/2018The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes.
11/2017Assessment of ELISA as endpoint in neuronal cell-based assay for BoNT detection using hiPSC derived neurons.
10/2017Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
1/2017Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A.
2/2016A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin.
1/2016Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified Clostridium botulinum Strain.
7/2015Activity of botulinum neurotoxin type D (strain 1873) in human neurons.
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William H Tepp Research Topics

Disease

32Botulism
01/2021 - 09/2003
10Paralysis (Palsy)
01/2015 - 09/2003
4Tetanus
11/2020 - 11/2010
2Infections
11/2020 - 08/2015
2Nervous System Diseases (Neurological Disorders)
01/2011 - 10/2007
1Parkinson Disease (Parkinson's Disease)
08/2015
1Alzheimer Disease (Alzheimer's Disease)
08/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2015
1Muscle Spasticity (Spastic)
10/2014
1Neuroblastoma
02/2014
1Inflammation (Inflammations)
12/2011
1Chronic Disease (Chronic Diseases)
12/2011
1Anthrax
04/2009
1Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature
04/2009

Drug/Important Bio-Agent (IBA)

25Botulinum Toxins (Botulinum Toxin)IBA
01/2021 - 09/2003
11Pharmaceutical PreparationsIBA
12/2019 - 10/2007
7NeurotoxinsIBA
09/2019 - 10/2007
7incobotulinumtoxinAFDA Link
01/2018 - 01/2008
6Proteins (Proteins, Gene)FDA Link
11/2020 - 09/2003
6Neurotransmitter Agents (Neurotransmitter)IBA
10/2018 - 09/2003
4VaccinesIBA
11/2020 - 01/2008
4SNARE Proteins (SNAREs)IBA
10/2018 - 12/2013
4AntitoxinsIBA
10/2017 - 12/2014
3tetanospasmin (tentoxilysin)IBA
02/2014 - 11/2010
2Tetanus ToxinIBA
10/2014 - 04/2009
2Biological Warfare AgentsIBA
05/2012 - 09/2011
1Conjugate VaccinesIBA
11/2020
1Polysaccharides (Glycans)IBA
11/2020
1AcidsIBA
01/2018
1Vesicle-Associated Membrane Protein 2 (VAMP2)IBA
10/2014
1GangliosidesIBA
02/2014
1Peptide Hydrolases (Proteases)FDA Link
10/2013
1Virulence Factors (Pathogenicity Factors)IBA
07/2013
1ToxoidsIBA
07/2013
1methylallyl trisulfide (MATS)IBA
03/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2011
1CytokinesIBA
12/2011
1toosendaninIBA
09/2011
1Therapeutic UsesIBA
09/2011
1Peptides (Polypeptides)IBA
04/2009
1Type A Botulinum Toxins (Botox)FDA Link
04/2009
1Synaptosomal-Associated Protein 25IBA
04/2009
1EnzymesIBA
04/2009
1botulinum toxin type EIBA
12/2008
1Subunit VaccinesIBA
03/2008
1Bacterial ToxinsIBA
12/2006

Therapy/Procedure

1Lab-On-A-Chip Devices
01/2016
1Therapeutics
08/2015